Worm Watch Lab Talk

motor defects

  • 2ndgm by 2ndgm

    what exactly is wrong with these worms that don't move normally?

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  • WEBs_in_space by WEBs_in_space

    This armchair 'scientist' had found or was told it is an UNC-7 gene in the worm. UNC-7 I tag them as #unc

    Stay cool

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  • 2ndgm by 2ndgm

    I obviously don't know anything about genetics or biology, but this looks different from the kinking and coiling. How does the same genetic defect cause different motor problems? This almost looks like an injury of some kind.

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  • Quia by Quia moderator

    I need some victory fanfare, here! Of all the things I was hoping to find, several hundred gene/strain labeled videos of c elegans was not even on the list because of how unlikely it was. 😄

    https://www.youtube.com/user/wormbehavior/videos

    Look familiar? They should, they're collected with the same hardware/software as the videos we're watching. Different worms, though, so not all the mutations we see are in this set and vis versa. This mutation looks rather unique with the funky smeared out trails, so I went for a quick browse through all the videos on that channel. And here she is! https://www.youtube.com/watch?v=Im45LMGjlhc

    Searching for that gene/strain nets me a lot of head-spinningly complex information about the mutation, this one is almost readable by normal human beings. 😃

    unc-38 I − 0.55 e264
    : weak kinker, sluggish, slightly dumpyish, sometimes Egl; resistant to 1 mm levamisole in body but not in head; sensitive to hypo-osmotic shock. ES3 ME2. OA>40: e213, e743, x20, etc. cloned: encodes subunit of nicotinic acetylcholine receptor.

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  • 2ndgm by 2ndgm

    Thank you. Do you hear the trumpets? It was interesting to see a longer video. The next two videos were good too; P. pacificus eats C. elegans, and C. elegans Harlem shake. I'm afraid the unc-381 stuff goes right by me though.

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  • DZM by DZM admin in response to 2ndgm's comment.

    C. elegans Harlem shake

    what :p

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  • Quia by Quia moderator in response to DZM's comment.

    @DZM My reaction too when I saw it. 😄

    https://www.youtube.com/watch?v=BWCm20gXnEs

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  • DZM by DZM admin in response to Quia's comment.

    wow

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